Very late thrombosis after drug-eluting stents
β Scribed by Fausto Feres; J. Ribamar Costa Jr.; Alexandre Abizaid
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 371 KB
- Volume
- 68
- Category
- Article
- ISSN
- 1522-1946
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Stent thrombosis is a rare but potentially fatal complication of percutaneous treatment of coronary disease. Its occurrence after drug eluting stent (DES) placement has raised concerns, especially when it occurs late after the stent implantation. The mechanisms of late thrombosis after DES have yet to be completely understood. By means of serial angiography and intravascular (IVUS) images we described a relatively new and unusual vessel response to drugβeluting stents (e.g. huge positive remodeling in all vessel extension), leading to impressive lateβacquired incomplete stent apposition and finally causing stent thrombosis and acute myocardial infarction. After describing the two cases, one after Cypher stent implantation and one after Taxus stent implantation, we briefly reviewed the literature available on stent thrombosis with special emphasis on its late occurrence. Β© 2006 WileyβLiss, Inc.
π SIMILAR VOLUMES
We describe two patients with in-stent thrombosis occurring 4 and 21 months after implantation of sirolimus-eluting stents. Both cases occurred following noncardiac surgery. In both cases, aspirin had been stopped prior to surgery. Both patient sustained a severe myocardial infarction; one died. The
## Abstract Background: Stent thrombosis (ST) risk may persist long after a successful drug eluting stents (DES) implantation. Objective:We evaluated the incidence, timing, and clinical outcomes of patients with early (β€30 days), late (>30β365 days), and very late (>365 days) angiographically prove