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Vertebrate Eye Development

✍ Scribed by Barbara Sivak, Jacob Sivak (auth.), M. Elizabeth Fini Ph. D. (eds.)


Publisher
Springer-Verlag Berlin Heidelberg
Year
2000
Tongue
English
Leaves
299
Series
Results and Problems in Cell Differentiation 31
Edition
1
Category
Library

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✦ Synopsis


The power of molecular genetics has recently returned the discipline of Developmental Biology to its original position at the forefront of biological research. The vertebrate eye was one of the classic embryologic models in the early 1900s. Within the last decade of the 20th century, a return to some of the old questions with the new approaches has put eye development back into the limelight. This book provides an up-to-date and comprehensive overview of the field. The latest advances in delineating genetic hierarchies for eye development in animals are discussed, as well as their relationship to congenital disorders of the eye which affect humans. Since studies in Drosophila have provided significant insight, chapters on this invertebrate model are included. In addition, a number of related areas are discussed which are unique to this book: developmental anatomy of the eye from the perspective of its optical function, recent advances in understanding how the retina connects to the brain, the role of extracellular matrix and cell adhesion molecules in eye development, and two chapters on eye regeneration in amphibians and fish.

✦ Table of Contents


Front Matter....Pages I-XIV
Vertebrate Eye Development and Refractive Function: An Overview....Pages 1-14
Pax6 and the Genetic Control of Early Eye Development....Pages 15-36
Early Retinal Development in Drosophila ....Pages 37-50
Induction of the Lens....Pages 51-68
Molecular Control of Cell Diversification in the Vertebrate Retina....Pages 69-91
Cell Fate Specification in the Drosophila Retina....Pages 93-114
Roles of the Extracellular Matrix in Retinal Development and Maintenance....Pages 115-140
Adhesive Events in Retinal Development and Function: The Role of Integrin Receptors....Pages 141-156
Connecting the Eye with the Brain: The Formation of the Retinotectal Pathway....Pages 157-177
Regeneration of the Lens in Amphibians....Pages 179-196
How the Neural Retina Regenerates....Pages 197-218
Mouse Mutants for Eye Development....Pages 219-256
Genetic Analysis of Eye Development in Zebrafish....Pages 257-282
Back Matter....Pages 283-288

✦ Subjects


Developmental Biology; Neurobiology; Cell Biology; Biochemistry, general


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