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Versatility of the mouse reversal/set-shifting test: Effects of topiramate and sex

โœ Scribed by Bissonette, Gregory B.; Lande, Michelle D.; Martins, Gabriela J.; Powell, Elizabeth M.


Book ID
119347566
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
458 KB
Volume
107
Category
Article
ISSN
0031-9384

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โœ Grahame Bulfield; Andrew Nahum ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer ๐ŸŒ English โš– 476 KB

The mouse mutants testicular feminization and sex reversal have been used to investigate hormone-mediated induction and repression of enzymes. Tfm/Y animals were already known to be androgen insensitive, rendering the androgen-inducible enzymes ADH and beta-glucuronidase noninducible because of an i