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Verbal aggression in Alzheimer's disease. Clinical, functional and neuropsychological correlates

✍ Scribed by A. Eustace; N. Kidd; E. Greene; C. Fallon; S. Ni Bhrain; C. Cunningham; R. Coen; J. B. Walsh; D. Coakley; B. A. Lawlor

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
56 KB
Volume
16
Category
Article
ISSN
0885-6230

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✦ Synopsis

Abstract

Objectives

To determine the clinical, functional and neuropsychological correlates of verbal aggression in Alzheimer's disease in a group of consecutive first attendees to a memory clinic.

Methods

150 people were evaluated and diagnosed as suffering with probable Alzheimer's disease. These people were tested using the Behave‐AD for the presence of verbal aggression, delusions, depression and agitation. They were also assessed with cognitive, functional and neuropsychological scales.

Results

Twenty‐eight per cent of this group of Alzheimer patients had exhibited some verbal aggression in the preceding month. Male gender (p = 0.022), the presence of paranoid and delusional ideation (p = 0.003) and agitation (p = 0.042) were significantly associated with verbal aggression in a stepwise backward logistic regression analysis.

Conclusion

The presence of verbal aggression should prompt the clinician to search for delusional ideation, which may respond to phamacotherapy. Copyright Β© 2001 John Wiley & Sons, Ltd.

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