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Verapamil inhibits ATP-sensitive potassium channel activation in the coronaries

✍ Scribed by Alexander Juhász-Nagy; Violetta Kékesi

Book ID
117142096
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
127 KB
Volume
34
Category
Article
ISSN
0022-2828

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✍ Bruno Allard; Michel Lazdunski 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 831 KB

Patch-clamp techniques were used to study the effects of internal nucleotide diphosphates on the KAT e channel in mouse skeletal muscle. In inside-out patches, application of GDP (100 gM) and ADP (100 gM) reversibly increased the channel activity. In the presence of internal Mg 2+ (1 mM), low concen