Venoms from six species of marine fish: lethal and hemolytic activities and their neutralization by commercial stonefish antivenom
✍ Scribed by K. Shiomi; M. Hosaka; S. Fujita; H. Yamanaka; T. Kikuchi
- Book ID
- 104756121
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 504 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0025-3162
No coin nor oath required. For personal study only.
✦ Synopsis
A specimen of the stone fish Synanceja verrucosa was captured in Okinawa in March 1988. Live specimens of the scorpionfish lnimicus japonicus were purchased from the Tokyo Central Wholesale Market in November 1988 and those of four species of zebrafish Pterois lunulata, P. volitans, P. antennata and Dendrochirus zebra from an aquarium in December 1988. Crude venoms were extracted from dorsal spines of the six species. All venoms exhibited lethal activity against mice and hemolytic activity specific for rabbit erythrocytes. The lethal activity (or hemolytic activity) of each venom was very unstable to freezing, lyophilization and heating. Both lethal and hemolytic activities of S. verrucosa venom were remarkably neutralized by the commercial stonefish (Synanceja trachynis) antivenom. This antivenom was also effective, to some extent, in counteracting the other venom activities. The neutralizing capacities of the antivenom were calculated to be 7310 LDso ml-1 for S. verrucosa venom and I 220 to 2 990 LDs0 ml-1 for the other venoms. Results of neutralization tests suggest that venoms from the six species were comparable in terms of antigenecity.