Velocity and Stability of Solitary Planar Travelling Wave Solutions of Intracellular [Ca]2+

✍ Scribed by G.C. Chopra; B.D. Sleeman; J. Brindley; D.G. Knapp; A.V. Holden

• Book ID: 102566494
• Publisher: Springer
• Year: 1999
• Tongue: English
• Weight: 386 KB
• Volume: 61
• Category: Article
• ISSN: 1522-9602
• DOI: 10.1006/bulm.1998.0081

✦ Synopsis

Normal cardiac muscle contraction occurs in response to a rapid rise followed by a slower decay in intracellular calcium concentration. When cardiac muscle cells are loaded with calcium, an intracellular store releases calcium into the cytosol by the process of calcium-induced calcium release (CICR). This release contributes to the rise in intracellular calcium which in turn triggers contraction. We use two qualitative piecewise linear reaction-diffusion models of this behaviour to investigate the speed, stability and waveform of plane waves using singular perturbation techniques.