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VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer

✍ Scribed by Reija Valtola; Petri Salven; Päivi Heikkilä; Jussi Taipale; Heikki Joensuu; Marko Rehn; Taina Pihlajaniemi; Herbert Weich; Robert deWaal; Kari Alitalo

Book ID: 117022679
Publisher: American Society for Investigative Pathology
Year: 1999
Tongue: English
Weight: 443 KB
Volume: 154
Category: Article
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)65392-8

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Angiogenesis is esential for tumour growth and metastasis. Vascular endothelial growth factor (VEGF) is a potent endothelial cell mitogen and is an important component of the angiogenic stimulus in a range of human neoplasias. In addition to its mitogenic activities, VEGF has also been found to stim