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VEGF receptor antisense therapy inhibits angiogenesis and peritoneal dissemination of human gastric cancer in nude mice

✍ Scribed by Kamiyama, Masako; Ichikawa, Yasushi; Ishikawa, Takashi; Chishima, Takashi; Hasegawa, Satoshi; Hamaguchi, Yohei; Nagashima, Yoji; Miyagi, Yohei; Mitsuhashi, Masato; Hyndman, David

Book ID: 110018868
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 446 KB
Volume: 9
Category: Article
ISSN: 0929-1903
DOI: 10.1038/sj.cgt.7700428

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## Abstract Vascular endothelial growth factor (VEGF) is the major pro‐angiogenic factor for most tumors. VEGF expression has been shown to be associated with a poor prognosis in human pancreatic cancer. The purpose of our study was to determine the effect of blockade of VEGF receptor‐2 activity wi