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VEGF and bFGF expression and microvessel density of maxillary sinus squamous cell carcinoma in relation to p53 status, spontaneous apoptosis and prognosis

✍ Scribed by Nobuyuki Bandoh; Tatsuya Hayashi; Miki Takahara; Kan Kishibe; Takeshi Ogino; Akihiro Katayama; Masanobu Imada; Satoshi Nonaka; Yasuaki Harabuchi


Book ID
116332997
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
347 KB
Volume
208
Category
Article
ISSN
0304-3835

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Mutation of p53 in head and neck squamou
✍ Genevieve A. Andrews; Sichuan Xi; Rebecca G. Pomerantz; Charles J. Lin; William πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 515 KB

## Abstract ## Background. The p53 protein, a well‐known tumor suppressor that functions primarily as a transcription factor, initiates cell cycle arrest and apoptosis after genotoxic stress. The antiapoptotic regulator Bcl‐2 is a downstream modulator of p53‐induced apoptosis. Loss of function of