VEGF165 mediates formation of complexes
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Shay Soker; Hua-Quan Miao; Masashi Nomi; Seiji Takashima; Michael Klagsbrun
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Article
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2002
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John Wiley and Sons
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English
β 336 KB
Co-expression of NRP1 and (VEGFR-2) KDR on the surface of endothelial cells (EC) enhances VEGF165 binding to KDR and EC chemotaxis in response to VEGF165. Overexpression of NRP1 by prostate tumor cells in vivo results in increased tumor angiogenesis and growth. We investigated the molecular mechanis