Vector systems of RNA interference
β Scribed by K. Yu. Kazachenko; P. V. Avdonin
- Book ID
- 110213498
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 191 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1062-3604
No coin nor oath required. For personal study only.
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## Abstract While traditional metabolic engineering generally relies on the augmentation of specific genes and pathways in order to increase the yield of target proteins, the advent of RNA interference (RNAi) as a biological tool has given metabolic engineers another tool capable of rationally alte
## Abstract ## Background Viral vectors have been used in several different settings for the delivery of small hairpin (sh) RNAs. However, most vectors have utilized ubiquitouslyβexpressing polymerase (pol) III promoters to drive expression of the hairpin as a result of the strict requirement for