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VAV1 represses E-cadherin expression through the transactivation of Snail and Slug: a potential mechanism for aberrant epithelial to mesenchymal transition in human epithelial ovarian cancer

✍ Scribed by Wakahashi, Senn; Sudo, Tamotsu; Oka, Noriko; Ueno, Sayaka; Yamaguchi, Satoshi; Fujiwara, Kiyoshi; Ohbayashi, Chiho; Nishimura, Ryuichiro


Book ID
122557803
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
990 KB
Volume
162
Category
Article
ISSN
1931-5244

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Loss of MKK4 expression in ovarian cance
✍ Shamima Yeasmin; Kentaro Nakayama; Mohammed Tanjimur Rahman; Munmun Rahman; Masa 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 697 KB

## Abstract In the current study, we investigated the mechanism relating downregulation of mitogen‐activated protein kinase kinase 4 (MKK4) expression to development of ovarian cancer. Over‐expression of the MKK4 gene in TOV‐21 G cells, a line with homozygous deletion of MKK4, resulted in morpholog