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Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery

✍ Scribed by Toru Yasutsune; Nozomi Kawakami; Katsuya Hirano; Junji Nishimura; Hisataka Yasui; Kenji Kitamura; Hideo Kanaide


Book ID
110004095
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
417 KB
Volume
126
Category
Article
ISSN
0007-1188

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The Ξ±1-agonist phenylephrine inhibits vo
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The effects of the alpha 1-agonist phenylephrine on the voltage-gated Ca2(+)-entry in vascular smooth muscle cells has been studied by measuring the agonist-induced changes of [Ca2+]i in K(+)-depolarized tissues. These changes have been estimated from the changes in fluorescence of the Ca2(+)-indica