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Vasomotor dysfunction in carpal tunnel syndrome

✍ Scribed by Einar P.V. Wilder-Smith; Stephanie Fook-Chong; Soh Eng Chew; Adeline Chow; Yaling Guo

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
94 KB
Volume
28
Category
Article
ISSN
0148-639X

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✦ Synopsis

Abstract

Little attention has been paid to small‐fiber dysfunction in carpal tunnel syndrome (CTS) although its symptoms are common. This study investigates vasomotor dysfunction, which is controlled by small nerve fibers, in patients with CTS compared with control subjects. Vasomotor function was quantified by measuring, with laser Doppler velocimetry, skin vasoconstriction induced by a eutectic mixture of local anesthetic (EMLA) cream over digit tips 3, 4, and 5. Hands with CTS (n = 32) compared with controls (n = 19) demonstrated significantly reduced vasoconstriction in digits 3 and 4, but not digit 5. A blood flow ratio (digit 3/5) of less than 0.73 identified CTS in 69% with 68% specificity. Testing for vasomotor dysfunction in CTS allows for more comprehensive neurophysiological testing, which is heavily biased towards large nerve fibers. Muscle Nerve 28: 582–586, 2003

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