Vasodilator effects of adrenomedullin on small pulmonary arteries and veins in anaesthetized cats
โ Scribed by Mikiyasu Shirai; Akito Shimouchi; Soichiro Ikeda; Ishio Ninomiya; Kenji Sunagawa; Kenji Kangawa; Hisayuki Matsuo
- Book ID
- 110002967
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 402 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0007-1188
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๐ SIMILAR VOLUMES
In small (less than 300 microns diameter) pulmonary arterial (PA) rings isolated from the cat, hypoxia induced a transient contraction (250 +/- 120 mg, n = 7), whereas in rings of rabbit PA of the same size, hypoxia had no significant effect (n = 19). Precontraction by 40 mmol KCl.1(-1), noradrenali
SUMMARY: The influence of melatonin on tension of isolated pulmonary vascular smooth muscle rings was examined in these experiments. Melatonin caused a dose-dependent relaxation of precontracted \((30 \mathrm{mM} \mathrm{KCl})\) pulmonary artery and pulmonary vein. Removal of the endothelium did not