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Vasodilating effect of norethisterone and its 5α metabolites: a novel nongenomic action

✍ Scribed by Mercedes Perusquı́a; Carlos M Villalón; Erika Navarrete; Gustavo A Garcı́a; Gregorio Pérez-Palacios; Ana E Lemus

Book ID
114015847
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
289 KB
Volume
475
Category
Article
ISSN
0014-2999

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Molecular mechanisms of the antihormonal
Molecular mechanisms of the antihormonal and antiimplantation effects of norethisterone and its a-ring reduced metabolites
✍ Ivone Castro; Marco Antonio Cerbón; Ana Maria Pasapera; Ruben GutiéRrez-sagal; G 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 692 KB

## Abstract Norethisterone (NET) has been used as a contragestational postcoital agent. It is biotrans‐formed to 5α dihydro‐NET (5α‐NET) and 3β,5α tetrahydro‐NET (3β,5α‐NET) in target tissues. The participation of these metabolites in NET effects is unknown. We have examined the antiimplantation an