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Vasoconstrictor-induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells

โœ Scribed by Terutaka Tsuda; Yasuhiro Kawahara; Kozui Shii; Masanobu Koide; Yoshihiro Ishida; Mitsuhiro Yokoyama


Book ID
115924994
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
677 KB
Volume
285
Category
Article
ISSN
0014-5793

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Aberrant vascular smooth muscle cell (VSMC) hyperplasia is the hallmark of atherosclerosis and restenosis seen after vascular surgery. Heparin inhibits VSMC proliferation in animal models and in cell culture. To test our hypothesis that heparin mediates its antiproliferative effect by altering phosp