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Vasoactive intestinal contractor (VIC): Its function in the guinea pig ileum and expression of VIC receptors in Xenopus oocytes

✍ Scribed by Yoshida, Shigeru; Yoshimura, Mizuko; Kan, Shukei; Niwa, Masami; Taniyama, Kohtaro


Book ID
122514484
Publisher
Elsevier Science
Year
1992
Weight
124 KB
Volume
17
Category
Article
ISSN
0921-8696

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Actions of dolasetron and its major meta
✍ Robert Dumaine; Hali A. Hartmann; Derek J. Leishman; Arthur M. Brown; Martin Gal πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 695 KB

The present study evaluated the effects of the anti-emetic 5-HT3 antagonist dolasetron and its major metabolite MDL 73,405 on guinea-pig papillary muscle fibres and human heart sodium channels expressed in Xenopus oocytes. Dolasetron and MDL 73,405 (3-10 p M ) reduced the maximum depolarization rate