Vasoactive effect of cyclosporine on the rat peribiliary capillary plexus: relationship with cholestasis and hyperbilirubinemia

Inhibition of hepatocytary vesicular tra

Inhibition of hepatocytary vesicular transport by cyclosporin a in the rat: Relationship with cholestasis and hyperbilirubinemia

✍ Irene D. Roman; Maria J. Monte; Jose M. Gonzalez-Buitrago; Alejandro Esteller; P 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 934 KB

In an attempt to understand the hepatotoxicity associated with immunosuppressive therapy with cy- cloeporin A, we inveatigated the effects of acute cyclosporin A admidstration on biliary secretion, serum bile acid and bilirubin levels and the hietological changes in the hepatic parenchyma in anemthe