𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Vascular reorganization and return of rigidity in fracture healing

✍ Scribed by L. Chidgey; D. Chakkalakal; A. Blotcky; Dr. J. F. Connolly

Book ID
102912698
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
683 KB
Volume
4
Category
Article
ISSN
0736-0266

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✦ Synopsis

The present study addresses the relationship between vascular reorganization and the biomechanical changes occurring during canine long bone fracture healing. A rniddiaphyseal osteotorny of the radius was performed, and angiographic studies were carried out using India ink injections from 2 to 12 weeks postosteotomy. The radii were harvested, subjected to nondestructive four-point bend testing on an Instron, and then sectioned and cleared according to the Spaltholtz technique. The observed microangiographic patterns were correlated with the calculated rigidity values. Quantitative bone blood flow measurements around the osteotomy were performed on a different group of animals, using the radiotracer microsphere technique, at 3, 6, and 9 weeks postosteotorny to correlate with our qualitative rnicroangiographic results. We demonstrated a direct and predictable relationship between the phase of vascular reorganization and the rigidity. This correlation was present even in our delayed union specimens.

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