Vascular permeability of pancreatic islets after administration of streptozotocin
โ Scribed by Sandler, S. ;Jansson, L.
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 980 KB
- Volume
- 407
- Category
- Article
- ISSN
- 0174-7398
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๐ SIMILAR VOLUMES
## Abstract Our objective was to study the effects of three (30, 40, and 50 mg/kg) doses of Streptozotocin (STZ) on fasting plasma glucose level (FPG) and observe its effects at the cellular level in rat pancreas by electron microscopy. FPG was measured in rats before induction of diabetes and then
Background: Streptozotocin (STZ) is selectively toxic to the B cells in the pancreatic islets. It is well known that in the adult rat, STZ causes the death of B cells, and it eventually induces diabetes mellitus. The present study was conducted to detect what morphological changes could be induced i
Pancreatic islets of the Syrian golden hamster were maintained in culture for extended periods of time. Toxicity of streptozotocin in these cultures was evaluated by measurement of insulin secretion. Exposure of islets to 1 or 2 mM streptozotocin immediately following isolation resulted in a permane