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Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells

✍ Scribed by Watanabe, Yoshifumi; Lee, Sam W; Detmar, Michael; Ajioka, Itsuki; Dvorak, Harold F


Book ID
110060653
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
899 KB
Volume
14
Category
Article
ISSN
0950-9232

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Vascular endothelial growth factor (VECF) is a 45kDa secreted peptide that has potent mitogenic activity specific for endothelial cells in vitro and the ability to induce a strong angiogenic response in vivo. In the present study, 24 h treatment with VEGF resulted in a stimulation of expression of t