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Vascular hemichorea/hemiballism and topiramate

✍ Scribed by Emilia Mabel Gatto; Claudia Uribe Roca; Gabriela Raina; Marcelo Gorja; Silvia Folgar; Federico E. Micheli

Book ID
102945078
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
865 KB
Volume
19
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Although vascular hemichorea/hemiballism (HC/HB) has been reported to be self‐limited, in some cases, it can be irreversible and severely disabling. The standard treatment includes typical and atypical neuroleptics and GABA‐mimetic drugs. Topiramate is a new antiepileptic drug possessing a complex mechanism of action, including the enhancement of GABA‐mediated inhibition. We describe a 71‐year‐old patient with HC/HB who markedly improved after topiramate treatment. © 2004 Movement Disorder Society

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