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Vascular endothelial growth factor protects hepatoma cells against oxidative stress-induced cell death

✍ Scribed by Shinji Osada; Hisashi Imai; Hiroyuki Tomita; Yasuharu Tokuyma; Naoki Okumura; Fumio Sakashita; Kenichi Nonoka; Yasuyuki Sugiyama


Book ID
108950711
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
218 KB
Volume
21
Category
Article
ISSN
0815-9319

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Vascular endothelial growth factor (VECF) is a 45kDa secreted peptide that has potent mitogenic activity specific for endothelial cells in vitro and the ability to induce a strong angiogenic response in vivo. In the present study, 24 h treatment with VEGF resulted in a stimulation of expression of t