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Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells

✍ Scribed by Frauke Forstreuter; Ralph Lucius; Rolf Mentlein

Book ID
114137767
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
338 KB
Volume
132
Category
Article
ISSN
0165-5728

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Vascular endothelial growth factor (VECF) is a 45kDa secreted peptide that has potent mitogenic activity specific for endothelial cells in vitro and the ability to induce a strong angiogenic response in vivo. In the present study, 24 h treatment with VEGF resulted in a stimulation of expression of t