## Abstract Retinal pigment epithelial (RPE) cells secrete vascular endothelial growth factor (VEGF), a cytokine known to promote angiogenesis. Results from RNase protection assays (RPAs) show that RPE from nonβdiabetic human donors and from adult retinal pigment epitheliumβ19 (ARPEβ19) cells expre
Vascular endothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase C-dependent
β Scribed by Tara A. Young; Hong Wang; Snezana Munk; Dena S. Hammoudi; Diana S. Young; Mark S. Mandelcorn; Catharine I. Whiteside
- Book ID
- 116456125
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 649 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0014-4835
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## Abstract Vascular endothelial growth factor (VEGF) is a major agent in choroidal and retinal neovascularization, events associated with ageβrelated macular degeneration (AMD) and diabetic retinopathy. Retinal pigment epithelium (RPE), strategically located between retina and choroid, plays a cri
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