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Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs

✍ Scribed by S. E. Cross; S. K. Richards; A. Clark; A. V. Benest; D. O. Bates; P. W. Mathieson; P. R. V. Johnson; S. J. Harper; R. M. Smith


Book ID
105818784
Publisher
Springer
Year
2007
Tongue
English
Weight
298 KB
Volume
50
Category
Article
ISSN
0012-186X

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## Abstract Vascular endothelial growth factor‐D (VEGF‐D) stimulates growth of vascular and lymphatic endothelial cells by signaling through the tyrosine kinase receptors KDR (VEGFR‐2) and Flt‐4 (VEGFR‐3). In the present study, we examined the effects of VEGF‐D on apoptosis in human MCF‐7 and MDA‐M