Vascular endothelial growth factor and breast cancer risk
β Scribed by Katherine W. Reeves; Roberta B. Ness; Roslyn A. Stone; Joel L. Weissfeld; Victor G. Vogel; Robert W. Powers; Francesmary Modugno; Jane A. Cauley
- Publisher
- Springer Netherlands
- Year
- 2008
- Tongue
- English
- Weight
- 246 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0957-5243
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## Abstract A common 936 C/T polymorphism in the gene for the vascular endothelial growth factor (VEGF) has been associated with VEGF plasma levels. In our caseβcontrol study, we investigated the role of this polymorphism for breast cancer risk. VEGF genotype was determined in 500 women with breast
## BACKGROUND. Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth fa