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VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

✍ Scribed by Koboldt, D. C.; Zhang, Q.; Larson, D. E.; Shen, D.; McLellan, M. D.; Lin, L.; Miller, C. A.; Mardis, E. R.; Ding, L.; Wilson, R. K.

Book ID
121340968
Publisher
Cold Spring Harbor Laboratory Press
Year
2012
Tongue
English
Weight
682 KB
Volume
22
Category
Article
ISSN
1088-9051

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VarScan 2: Somatic mutation and copy num
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
✍ Koboldt, D. C.; Zhang, Q.; Larson, D. E.; Shen, D.; McLellan, M. D.; Lin, L.; Mi πŸ“‚ Article πŸ“… 2012 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 682 KB

Cancer is a disease driven by genetic variation and mutation. Exome sequencing can be utilized for discovering these variants and mutations across hundreds of tumors. Here we present an analysis tool, VarScan 2, for the detection of somatic mutations and copy number alterations (CNAs) in exome data