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Variation of the frameshift activity of a mutagen (ICR-191) following nitrosation in human gastric juice

โœ Scribed by De Flora, Silvio; De Flora, Antonio


Book ID
123056231
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
350 KB
Volume
11
Category
Article
ISSN
0304-3835

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The mutagenic activity of glycine upon nitrosation was studied in the Ames tester strains TA98, TA100, TA102, and TA104. The results obtained show that glycine at acidic pH values and in the presence of Cl- can react with nitrite giving rise to genotoxic compounds to the tester strains used. When th