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Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans

✍ Scribed by O. Tschritter; H. Preissl; Y. Yokoyama; F. Machicao; H.-U. Häring; A. Fritsche

Publisher
Springer
Year
2008
Tongue
English
Weight
41 KB
Volume
51
Category
Article
ISSN
0012-186X

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## Abstract The TREK1 gene has been linked to a depression‐resistant phenotype in rodents and antidepressant response in humans, but the neural mechanisms underlying these links are unclear. Because TREK1 is expressed in reward‐related basal ganglia regions, it has been hypothesized that TREK1 gene