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Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men

✍ Scribed by Yi-Hsiang Hsu; Tianhua Niu; Henry A. Terwedow; Xin Xu; Yan Feng; Zhiping Li; Joseph D. Brain; Cliff J. Rosen; Nan Laird; Xiping Xu


Publisher
Springer
Year
2005
Tongue
English
Weight
372 KB
Volume
118
Category
Article
ISSN
0340-6717

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Genetic variation in the RANKL/RANK/OPG
✍ Delnaz Roshandel; Kate L Holliday; Stephen R Pye; Steven Boonen; Herman Borghs; πŸ“‚ Article πŸ“… 2010 πŸ› American Society for Bone and Mineral Research 🌐 English βš– 220 KB πŸ‘ 1 views

## Abstract The aim of this study was to determine if single‐nucleotide polymorphisms (SNPs) in __RANKL__, __RANK__, and __OPG__ influence bone turnover and bone mineral density (BMD) in men. Pairwise tag SNPs (__r__^2^ β‰₯ 0.8) were selected for __RANKL__, __RANK__, and __OPG__ and their 10‐kb flank