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Variation in complement factor 3 is associated with risk of age-related macular degeneration

โœ Scribed by Maller, Julian B; Fagerness, Jesen A; Reynolds, Robyn C; Neale, Benjamin M; Daly, Mark J; Seddon, Johanna M


Book ID
109919638
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
110 KB
Volume
39
Category
Article
ISSN
1061-4036

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Progression of age-related macular degeneration (AMD), the leading cause of blindness in the elderly, was followed in a cohort of 238 individuals from a single center. Individuals with an epsilon (e)2 genotype (c.526C4T of reference sequence NM -000041.2) of the apolipoprotein (APOE) gene were found