Variation in Blood Levels of Inflammatory Markers Related and Unrelated to Smoking Cessation in Women

✍ Scribed by Christopher J.K. Hammett; Harry Prapavessis; J. Chris Baldi; Rohan Ameratunga; Uwe Schoenbeck; Nerea Varo; John K. French; Harvey D. White; Ralph A.H. Stewart

• Book ID: 115304780
• Publisher: Le Jacq Communications, Inc.
• Year: 2007
• Tongue: English
• Weight: 895 KB
• Volume: 10
• Category: Article
• ISSN: 1520-037X
• DOI: 10.1111/j.1520-037x.2007.05957.x

✦ Synopsis

This study assessed the influence of short‐term changes in smoking habit on blood levels of inflammatory markers, which have been associated with increased cardiovascular risk. Five inflammatory markers were measured before and 6 weeks after attempting smoking cessation in 138 healthy women. In the 48 participants who stopped smoking, white blood cell count (−0.7±1.2 × 10^9^/L; P__<.001) and fibrinogen (−0.6±1.5µmol/L;__ P__<.01) decreased, but there was no significant (P>.1) change in the plasma level of C‐reactive protein (median change +0.1; interquartile range −0.2, 0.9 mg/L), intercellular adhesion molecule 1 (+17±75 ng/mL), or CD40 ligand (+0.4±2.1 ng/mL). Most of the individual variation in inflammatory marker levels was unrelated to changes in smoking habit.__