Ricin A-chain conjugated with monoclonal
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Kazuo Kishida; Yasuhiko Masuho; Masahiko Saito; Takeshi Hara; Hiroshi Fuji
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Article
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1983
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Springer-Verlag
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English
โ 608 KB
In studies of antitumor antibody-cytotoxic agent conjugates as potential antitumor agents with improved tumor specificity, the toxic subunit A-chain of ricin was conjugated with a monoclonal antibody to a tumor-associated antigen expressed weakly on murine leukemia L1210 cells and strongly on L1210/