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Variants in the promoter region ofCYP7A1are associated with neuromyelitis optica but not with multiple sclerosis in the Han Chinese population

✍ Scribed by Gui-Xian Zhao, Ying Liu, Zhen-Xin Li, Chuan-Zhen Lv…

Book ID
120958584
Publisher
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Year
2013
Tongue
English
Weight
256 KB
Volume
29
Category
Article
ISSN
1673-7067

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## Abstract Interleukin 1β (IL‐1β) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (T‐31C and C‐511T) in the __IL‐1__β gene promote