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Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate

✍ Scribed by Hannah C. Cox; Rod A. Lea; Claire Bellis; Melanie Carless; Tom Dyer; John Blangero; Lyn R. Griffiths


Publisher
Springer
Year
2011
Tongue
English
Weight
217 KB
Volume
12
Category
Article
ISSN
1129-2369

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## Abstract A series of 121 human breast tumors was screened for point mutations in exons 5 through 8 of the p53 gene, by SSCP analysis. On the same tumor samples, the S‐phase index (SPI) was determined by the incorporation of BUdR in fresh tissue. p53 mutations were observed in 29% of the cases. T