Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancer
โ Scribed by Heather Greenlee; Yu Chen; Geoffrey C. Kabat; Qiao Wang; Muhammad G. Kibriya; Irina Gurvich; Daniel W. Sepkovic; H. Leon Bradlow; Ruby T. Senie; Regina M. Santella; Habibul Ahsan
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 188 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0167-6806
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Dr. Dupont has accepted honoraria for presenting papers at professional meetings from pharmaceutical firms that market hormonal replacement therapy. On three occasions in his career he has been a consultant for Wyeth-Ayerst Pharmaceuticals. The authors thank Marcia G. Freudenthal, Cheryl D. Sharpe,
## Abstract Estrogens exert their effect on the breast through the estrogen receptor. We prospectively investigated breast cancer risk associated with 2 polymorphic sites in the estrogen receptor alpha gene (__ESR1__). A total of 4,248 Caucasian women from the Study of Osteoporotic Fractures were g