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Variant Ph translocations in chronic myeloid leukemia

✍ Scribed by Heim, Sverre; Billström, Rolf; Kristoffersson, Ulf; Mandahl, Nils; Strömbeck, Bodil; Mitelman, Felix

Book ID
121930397
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
526 KB
Volume
18
Category
Article
ISSN
0165-4608

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## Abstract Leukemic cells from two patients with Philadelphia‐negative chronic myeloid leukemia (CML) were investigated: I) Cytogenetics showed a normal 46.XY karyotype in both cases, 2) molecular studies revealed rearrangement of the M‐BCR region and formation of __BCR‐ABL__ fusion mRNA with b2a2