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Variant metabolizing gene alleles determine the genotoxicity of benzo[a]pyrene

โœ Scribed by Salama A. Salama; Carlos H. Sierra-Torres; Hye Young Oh; Farid A. Hamada; William W. Au

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
156 KB
Volume
37
Category
Article
ISSN
0893-6692

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โœ Williams, H.J.; Bray, N.; Murphy, K.C.; Cardno, A.G.; Jones, L.A.; Owen, M.J. ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 7 KB ๐Ÿ‘ 2 views

Dopamine โค-hydroxylase (DBH), the enzyme that converts dopamine to norepinepherine, has been proposed as being involved in the aetiology of schizophrenia. Previous work identified a functional polymorphism at nucleotide 910 of the DBH gene that results in a codon change in the mature protein Ala304S