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Variant in the 3′ Region of the IκBα Gene Associated With Insulin Resistance in Hispanic Americans: The IRAS Family Study

✍ Scribed by Melissa R. Miller; Weiming Zhang; Scott P. Sibbel; Carl D. Langefeld; Donald W. Bowden; Steven M. Haffner; Richard N. Bergman; Jill M. Norris; Tasha E. Fingerlin

Book ID: 109969738
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 343 KB
Volume: 18
Category: Article
ISSN: 1930-7381
DOI: 10.1038/oby.2009.303

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## Abstract ## BACKGROUND: Tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NKK) is a well defined carcinogen that can induce lung cancer. Genetic polymorphisms in its disposition pathways could modify the risk of developing lung cancer. The authors of this report previ