Mutations at the ataxia-telangiectasia l
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Li, Airong; Swift, Michael
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Article
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2000
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John Wiley and Sons
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English
⚖ 61 KB
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## Mutations at the ataxia-telangiectasia (A-T) locus on chromosome band 11q22 cause a distinctive autosomal recessive syndrome in homozygotes and predispose heterozygotes to cancer, ischemic heart disease, and early mortality. PCR amplification from genomic DNA and automated sequencing of the enti