## Abstract ## Objective: Multiple sclerosis (MS) is a complex neurological disease. Genetic linkage analysis and genotyping of candidate genes in families with 4 or more affected individuals more heavily loaded for susceptibility genes has not fully explained familial disease clustering. ## Meth
Variant alleles of the CYP1B1 gene are associated with colorectal cancer susceptibility
✍ Scribed by Joanna Trubicka; Ewa Grabowska-Kłujszo; Janina Suchy; Bartłomiej Masojć; Pablo Serrano-Fernandez; Grzegorz Kurzawski; Cezary Cybulski; Bohdan Górski; Tomasz Huzarski; Tomasz Byrski; Jacek Gronwald; Elżbieta Złowocka; Józef Kładny; Zbigniew Banaszkiewicz; Rafał Wiśniowski; Elżbieta Kowalska; Jan Lubinski; Rodney J Scott
- Book ID
- 115010143
- Publisher
- BioMed Central
- Year
- 2010
- Tongue
- English
- Weight
- 422 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1471-2407
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## Abstract CYP1A1 is likely to play an important role in the etiology of CaP through its function in activating environmental procarcinogens and catalyzing the oxidative metabolites of estrogens. To test the hypothesis that genetic polymorphisms in the __CYP1A1__ gene may be associated with the ri