Estimation of sample size in clinical trials requires knowledge of parameters that involve the treatment effect and variability, which are usually uncertain to medical researchers. The recent release within the European Union of a Note for Guidance from the Commission for Proprietary Medical Product
โฆ LIBER โฆ
Variance Estimation in Clinical Studies with Interim Sample Size Reestimation
โ Scribed by Frank Miller
- Book ID
- 109223280
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 152 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0006-341X
No coin nor oath required. For personal study only.
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The performance of alternative biased estimators of population total in probability proportional to size sampling schemes is studied when the study variable has weak relationship with the size variable. A variety of natural populations are considered to study the performance of these estimators empi