Variable substructure in the secondary constriction of the human chromosome 1

✍ Scribed by J. Sigmund; S. Schwarz

• Book ID: 104700784
• Publisher: Springer
• Year: 1979
• Tongue: English
• Weight: 205 KB
• Volume: 46
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00278895

✦ Synopsis

The secondary constriction in human chromosome 1 consists of a proximal segment stained by the GC-specific fluorochrome mithramycin and a distal segment stained by such fluorochromes as DAPI or DIPI, which show enhanced fluorescence intensities in AT-rich regions of the chromosomes. A study involving 21 individuals revealed that both parts are independently involved in length variability. In two cases, two GC-rich regions separated by an AT-rich segment and an additional distal AT-rich part were found.