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Variable immunodeficiency with abnormal condensation of the heterochromatin of chromosomes 1, 9, and 16

✍ Scribed by Nancy J. Carpenter; Alexandra Filipovich; R. Michael Blaese; Terence L. Carey; A. Izzet Berkel


Book ID
119463395
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
859 KB
Volume
112
Category
Article
ISSN
1097-6833

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Centromeric heterochromatin instability
✍ Oskar A. Haas πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 275 KB

Centromeric instability of chromosomes 1, 9, and 16 has been described in eight patients with variable immunodeficiency. Although the pathogenetic relationship of these cytogenetic abnormalities with the clinical symptoms are unclear, it has nevertheless been proposed that they are a hallmark of thi