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Variable forms of soluble guanylyl cyclase: protein-ligand interactions and the issue of activation by carbon monoxide

โœ Scribed by Kathleen M. Vogel; Songzhou Hu; T. G. Spiro; Elizabeth A. Dierks; Anita E. Yu; J. N. Burstyn


Book ID
106233014
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
230 KB
Volume
4
Category
Article
ISSN
1432-1327

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Synergistic activation of soluble guanyl
โœ James R. Stones; Michael A. Marletta ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 880 KB

## Background: Nitric oxide (.no) is used in biology as both an intercellular signaling agent and a cytotoxic agent. in signaling, submicromolar quantities of .no stimulate the soluble isoform of guanylate cyclase (sgc) in the receptor cell. .no increases the vmax of this heterodimeric hemoprotein