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Variable Expression of the Translocated c-abl Oncogene in Philadelphia-Chromosome-Positive B-Lymphoid Cell Lines from Chronic Myelogenous Leukemia Patients

โœ Scribed by James B. Konopka, Steven Clark, Jami McLaughlin, Masakuzu Nitta, Yoshiro Kato, Annabel Strife, Bayard Clarkson and Owen N. Witte


Book ID
123633075
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
969 KB
Volume
83
Category
Article
ISSN
0027-8424

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The expression of c-abl, c-sis, c-myc and N-ras oncogenes was examined in 2 lymphoblastoid cell lines, one with Ph1 (PB-1049) and the other without Ph1 (LN-1049), both established from a patient with chronic myelogenous leukemia (CML), and in a Ph1-positive cell line (PB-1049-T) derived from a tumor