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Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

✍ Scribed by G Rose; S Dato; K Altomare; D Bellizzi; S Garasto; V Greco; G Passarino; E Feraco; V Mari; C Barbi; M BonaFe; C Franceschi; Q Tan; S Boiko; A.I Yashin; G De Benedictis

Book ID: 114253966
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 234 KB
Volume: 38
Category: Article
ISSN: 0531-5565
DOI: 10.1016/s0531-5565(03)00209-2

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## Abstract Killer‐cell Ig‐like receptors (KIR) are structurally and functionally diverse, and enable human NK cells to survey the expression of individual HLA class I molecules, often altered in infections and tumors. Multiple events of non‐reciprocal recombination have contributed to the rapid di